Automated insulin supply (AID) programs have helped many individuals with diabetes enhance their glucose administration and Time in Range, each throughout the day and in a single day. However, a current examine exhibits that utilizing the auto mode with the Medtronic 670G pump led to decrease sleep high quality in comparison with utilizing the handbook mode.
Advancements in diabetes know-how reminiscent of steady glucose screens (CGM) and automatic insulin supply (AID) programs, have helped many individuals with diabetes enhance their glucose administration and really feel safer and extra ready to deal with highs and lows.
While these gadgets can result in dramatic enhancements in glucose ranges, their impact on one other key side of diabetes administration, sleep, must be investigated. The ORACL examine, revealed in Diabetes Technology and Therapeutics on July 22, discovered an fascinating distinction in sleep high quality between utilizing the hybrid closed-loop auto mode with the Medtronic 670G pump (lately discontinued) in comparison with utilizing the handbook mode.
The trial included 60 members with kind 1 diabetes, focusing totally on older adults (all members have been age 60 and over). Everyone within the examine used a Medtronic MiniMed 670G insulin pump, and every participant was randomly assigned to make use of both the “auto” mode or “manual” mode. Auto mode incorporates glucose readings from the CGM and mechanically delivers insulin based mostly on glucose ranges. In distinction, handbook mode requires customers to manually bolus insulin, however can briefly droop insulin supply based mostly on glucose ranges to attempt to forestall hypoglycemia. During the 8-month examine, all members switched to the other group on the midway level (4 months).
Investigators measured sleep high quality utilizing an actigraph, a wearable machine that appears just like a wristwatch, that tracks motion, quantity of sleep, and different measures of sleep high quality. Participants have been additionally requested to maintain a diary for 2 weeks, to self-report after they went to mattress and awakened every day.
Over the course of the 8-month examine, these utilizing the auto mode setting had larger common Time in Range (90.3%) all through the night time than these utilizing the handbook mode (78.7%). The examine demonstrated that many of the glucose administration advantages from auto mode have been noticed after 4 hours of sleep. People on auto mode additionally skilled considerably fewer sensor alarms for hypoglycemia. Because this examine centered on glucose patterns throughout sleep, CGM readings throughout the day weren’t reported.
However, regardless of the larger period of time spent in vary, auto mode customers reported considerably decrease sleep high quality in comparison with handbook mode customers. Additionally, whereas the auto mode group had fewer alerts as a consequence of lows, the overall variety of alarms was really 30% larger on this group, presumably associated to hyperglycemia.
According to the examine’s authors, that is the first-ever randomized trial to supply proof that, throughout objectively-measured sleep, auto mode utilizing the 670G (a hybrid closed-loop AID system) improved time in vary and diminished the variety of hypoglycemia alerts in older adults with kind 1 diabetes.
More analysis is required on this space, however advances in AID programs and glucose monitoring know-how that result in fewer alarms, significantly for prime glucose ranges, might enhance sleep high quality in folks with kind 1 diabetes.
To study extra about methods to enhance your sleep, try these sources:
The Most Destructive Diabetes Landmine: Lack of Sleep?
High Blood Sugar at Night: What to Do
Type 1 & Type 2
Type 1 Diabetes News
Monday, August 1, 2022 – 14:34